Bring the immune system 
one step ahead of cancer

Off-the-shelf platform advancing next-generation in vivo immunotherapies to unlock immune response against solid tumors

THEY SUPPORT US

Redefining immuno-oncology through novel modalities

Mimicking cancer nature

A proprietary off-the-shelf platform, recapitulating both the spatial and temporal heterogeneity of the tumor, unveiling the broadest panel of cancer-associated antigens and rendering them visible to the immune system.

Scalable & cost efficient

Our platform applies precision medicine principles at large scale to improve outcomes, reduce costs, and address the needs of large patient populations facing limited therapeutic options.

Operational excellence

A team of seasoned leaders and innovators in immuno-oncology, backed by €40M in strategic funding.

Our focus: solid tumors  

Fast growing needs, insufficient solutions

90%

of patient face 
therapeutic failure

10Mdeaths

every year worldwide

The challenge

Cancer is a moving, heterogeneous & invisible target

Colorectal cancer (CRC) is the 2nd cause of cancer mortality worldwide,
and is defined by heterogeneity, plasticity and treatment resistances

95%

of patients have no other solution than outdated chemotherapies

12%

of patients survive after 5-year of treatment

For these patients: the immune system, natural body’s defenser, is blinded

No immune reaction can be initiated toward tumor cells
Inefficiency 
of classical immunotherapy

New therapeutic strategies are needed to restore anti-tumor immune response and capture cancer heterogeneity

Our solution:

Next-generation in vivo
immunotherapies

From “off-the-shelf” tumor banks to first-in-class immunotherapies
Enriched with the molecular fingerprints of tumor heterogeneity and resistances
Designed to unlock in vivo the immune system to fight back

Inspired by patients,
driven by science

Mimicking cancer to make it visible

We model solid tumors complexity using off-the-shelf cell lines, stimulated to reveal cancer-related proteins and validated by proteogenomic and predictive model.

These cells are then tagged with an immune flare (hapten), and inactivated into ghost cells to safely educate the immune system, to target evolving cancer cells and eradicate cancer.

From vision to execution

€30M

Invested since 2020

2

Clinical candidates advancing toward IND filing by 2027

9

Clinical sites open in 2027
Phase I/II for colorectal cancer patients in 1L
(US expansion planned)

100

patients treatable per batch
thanks to our standardized & scalable platform

2 388 000

Eligible patients by 2029

Latest news and research

January 22, 2026

Brenus Pharma reports favorable tolerability and clinical signals in early preliminary results of first-in-human study for STC-1010 in unresectable metastatic stage MSS CRC patients

READ the article
January 22, 2026

Le Monde – JPM26 Renewed euphoria in the biotech ecosystem

READ the article
January 22, 2026

BIO SPACE – Brenus Pharma Raises $25 Million to Accelerate Clinical Trials of Its Precision Anti-cancer immunotherapy

READ the article