An innovation to mimic patient’s cancer relapsing conditions.
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STC allogeneic vaccine
No tumor biopsy needed, No HLA restriction.
Mimicking patient’s mechanism of relapse to increase panel of targets. Validation based on proteome. (LC/MS)
Enhanced by hyphenation and ghost cells, maintaining safety.
“Off-the-shelf” standardized manufacturing, saving cost and time.
Invasive: tumor biopsy needed, HLA restriction.
Limited / Validation based on gene extrapolation. (NGC platform)
Non immunogenic targets, Potential safety issues with viral vectors.
“Patient / Patient”Complex, long and costly.
Brenus’ manufacturing process overpasses the lack of immunogenicity & educates the immune system with visible and multi-specific targets
Selection criteria of starting material (Allogeneic tumor cell lines)
Brenus’ manufacturing process overpasses the lack of antigenicity & educates the immune system with a broad & higher quality range of tumor antigens