J. Gardette

Serial Entrepreneur in Healthcare & Digital Health. He has founded 10+ companies in his career,  with successful exits: 6 of these being sold to large lifescience companies such as Bard, Baxter or Nipro Healthcare in various areas from Dialysis, Drug Delivery Devices or Cardiac Valves. Former funder and principal shareholder of Biocorp, now sold to Novo Nordisk for 154M€ Pioneer in innovative medicale devices,  and currently listed on Alternext Paris.

B. Pinteur

STC technology inventor Specialized in innovative cellular therapies Pharmaceutical development expert (Early R&D, QA/QC & development). Benoît Pinteur (Chief Scientific Officer, PharmD) brings 25 years of experience in the pharma industry with roles at Shering-Plough and Roche, mainly in pharmaceutical development. From previous collaboration with international teams on autologous cancer immunotherapy (ERC Belgium), he decided to create Brenus Pharma, with the STC Technology, to address previous limitations of immune therapeutics approach. Benoit was formerly the CEO of BioElpida, a CDMO where he developed expertise in ATMP and GMP manufacturing with a special focus on immunotherapies, cell therapies and vaccines.

P. Bravetti

Medical & Marketing expert Skills in Immuno-oncology : pharma product launches worldwide Paul Bravetti (PharmD, HEC Paris) is specialized in medical oncology and brings a wealth of experience from his international career at Roche, Servier, and Takeda Oncology, leading teams in Medical, Marketing, and Commercial functions. Paul has previously managed successful product launches in immuno-oncology including melanoma, lung cancer and bio-molecular diagnosis across EU and Asia.

A.Bordet

Experienced CFO in Health & Tech industries. Aymeric Bordet, (CCA, SKEMA) is an experienced CFO (from Seed to 100M$ Series B) in Health & Tech  innovative companies / SMEs and General Secretary in Angelor (VC Seed). Passionate about finance and innovation he wone the 2022 CFO trophy  DFCG Auvergne Rhône-Alpes.

L. Chalus

Pharmaceutical industry (R&D expert) & expertise in GMP Manufactruing . Lionel Chalus (Ingineer) brings 25 years of experience in the pharma industry with roles at Shering-Plough, Genopoïetic, Valneva, Bio-Elpida mainly in Research and pharmaceutical development and aquired a strong expertise in GLP/GMP manufacturing. Lionel has participated in the development of several drug candidates, particularly in cell therapies in the field of oncology and tissue regeneration.

C. Tortorelli

  Medical expertise in Oncology. Corinne Tortorelli (PharmD, Ph.D, former Hospital intern, SciencesPo. Paris) is specialized in solid tumors and onco-hematology with an expertise in Health Management and Policy. She brings a medical wealth of experience from her career at Novartis, Vifor Pharma and Takeda Oncology. And strong project management skills because of her position of Lead of international projects management to L’Oréal R&D during past years. Corinne has previously managed successful product development from early clinic to phase III and real-life clinical studies and participated to product launches in oncohematology (lymphoid and myeloid blood cancer) and in rare solid tumors.  

L.Perles

Business development, Licensing & Marketing skills in EU with Non-dilutive funding experiences. Léa Perles (PharmD, MSc) is specialized in external innovation & collaboration strategy, and benefits from various experiences in academic institutions and private companies in Europe, such as Sanofi Partnering. Léa has successfully negotiated and managed pharmaceutical partnership alliances across EU and led communication and management strategies.

M.Brun

Scientific valorization & Innovation Management skills. Marion Brun (Engineer,MSc) has various academic experiences in R&D project management in solid tumors (mostly pediatric). She brings scientific valorization & innovation management skills with her previous entrepreneurship & therapeutic innovation experiences. As scientific & innovation profile, Marion support external communication & technical valorization.

G.Alzeeb

Cancer Biology expert Specialist of 3D Culture Model & Multiomic analysis George Alzeeb (Ph.D) has a strong experience in pre-clinical research in academic sector, specialized in oncology. During academic experience (Ph.D candidate and PostDoc), he successfully developed several projects focusing on 3D cancer model. As scientific researcher, George, support research and development of drug candidates to valorize innovative projects, from study to clinical application.

INCREASE IMMUNOGENICITY

Brenus’ manufacturing process overpasses the lack of immunogenicity & educates the immune system  with visible and multi-specific targets

REPRESENT HETEROGENEITY OF THE TARGETED INDICATION

Selection criteria of starting material (Allogeneic tumor cell lines)

  • Representative oncogenic drivers (TP53,BRAF,KRAS,…)
  • Cold & hot tumor cell lines
  • Resistances capacities (metabolic ; chemical & physical)

Increase antigenicity

Brenus’ manufacturing process overpasses the lack of antigenicity & educates the immune system  with broad & higher quality range of tumor antigens